ethyl (2Z)-2-[(dimethylamino)methylidene]-3-oxobutanoate
Ethyl 2-acetyl-3-(dimethylamino)acrylate
CAS: 51145-57-4
Molecular Formula: C9H15NO3
ethyl (2Z)-2-[(dimethylamino)methylidene]-3-oxobutanoate - Names and Identifiers
ethyl (2Z)-2-[(dimethylamino)methylidene]-3-oxobutanoate - Physico-chemical Properties
| Molecular Formula | C9H15NO3 |
| Molar Mass | 185.22 |
| Density | 1.038±0.06 g/cm3(Predicted) |
| Melting Point | 41-44 °C(Solv: isopropyl ether (108-20-3)) |
| Boling Point | 128°C 0,2mm |
| Flash Point | 102.8°C |
| Vapor Presure | 0.0273mmHg at 25°C |
| Appearance | Liquid |
| Color | Pale red |
| Maximum wavelength(λmax) | ['304nm(EtOH(95vol%))(lit.)'] |
| pKa | 3.52±0.70(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,2-8°C |
| Refractive Index | 1.5330-1.5370 |
ethyl (2Z)-2-[(dimethylamino)methylidene]-3-oxobutanoate - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S23 - Do not breathe vapour. |
| Hazard Class | IRRITANT |
ethyl (2Z)-2-[(dimethylamino)methylidene]-3-oxobutanoate - Introduction
Ethyl 2-acetyl-3-(dimethylamino)acrylate is an organic compound with the formula C11H17NO3. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: colorless liquid
-Boiling point: 174-175 ℃
-Melting point:-12 ℃
-Density: 1.02 g/mL
-refractive index: 1.460-1.462
Use:
Ethyl 2-acetyl-3-(dimethylamino)acrylate main uses include:
-Used as an intermediate in organic synthesis, it can participate in esterification reactions and Michael addition reactions.
-In the medical field, it may be used as a synthetic precursor for certain drugs.
Preparation Method:
Ethyl 2-acetyl-3-(dimethylamino)acrylate is prepared as follows:
1.2-Acetyl ethyl acrylate is reacted with dimethylformamide to generate ethyl 2-acetyl -3-(dimethylamino) propionate.
2. catalyze the product with a certain amount of alkali for condensation reaction to obtain the final product Ethyl 2-acetyl-3-(dimethylamino)acrylate.
Safety Information:
- Ethyl 2-acetyl-3-(dimethylamino)acrylate need to take appropriate protective measures during storage and handling, such as wearing gloves, goggles and protective clothing.
-Avoid inhalation, contact with skin or eyes, such as inadvertent contact, immediately rinse with plenty of water, and seek medical advice.
-During storage and use, keep away from ignition and oxidizing agents, and pay attention to prevent leakage and exposure to other chemicals.
Please note that this is an organic compound, which needs to be used in accordance with laboratory safety practices and under the guidance of professionals.
Nature:
-Appearance: colorless liquid
-Boiling point: 174-175 ℃
-Melting point:-12 ℃
-Density: 1.02 g/mL
-refractive index: 1.460-1.462
Use:
Ethyl 2-acetyl-3-(dimethylamino)acrylate main uses include:
-Used as an intermediate in organic synthesis, it can participate in esterification reactions and Michael addition reactions.
-In the medical field, it may be used as a synthetic precursor for certain drugs.
Preparation Method:
Ethyl 2-acetyl-3-(dimethylamino)acrylate is prepared as follows:
1.2-Acetyl ethyl acrylate is reacted with dimethylformamide to generate ethyl 2-acetyl -3-(dimethylamino) propionate.
2. catalyze the product with a certain amount of alkali for condensation reaction to obtain the final product Ethyl 2-acetyl-3-(dimethylamino)acrylate.
Safety Information:
- Ethyl 2-acetyl-3-(dimethylamino)acrylate need to take appropriate protective measures during storage and handling, such as wearing gloves, goggles and protective clothing.
-Avoid inhalation, contact with skin or eyes, such as inadvertent contact, immediately rinse with plenty of water, and seek medical advice.
-During storage and use, keep away from ignition and oxidizing agents, and pay attention to prevent leakage and exposure to other chemicals.
Please note that this is an organic compound, which needs to be used in accordance with laboratory safety practices and under the guidance of professionals.
Last Update：2024-04-09 15:17:58
![ethyl (2Z)-2-[(dimethylamino)methylidene]-3-oxobutanoate](http://res.chembk.com/assets/str/2d/5/51/51145-57-4.png)